Are you a troll? Excuse me... a thoughtless child?

Just checking.

That checks out. I stopped cause it made me depressed.

Intuitively I want to say it is possible - any modification to DNA can potentially promote oncogenesis depending on how that affects gene expression and regulation of transcription. In this case, we don’t know yet.

Are you a crank? Just curious.

Exactly, but people who worship the meaningless term " all natural" and prostrate to the god of "organic" definitely don't spend much mental power with critical thinking. They spend more mental energy feeling vibes and talking to crystals.

I buy mostly organic but am not foolish enough to think it's some sort of panacea or that it automatically means something is healthy.

That's not what the research in the article says. The research is looking into the constant noise.

Yes, it’s actually surprising that we haven’t addressed this as a society, and bizarre antisocial actions are being seen as more or less normal. I have heard that some cities and countries are better at regulating this but unfortunately many of us do not live in civilised societies, and the existence of this behaviour is a clear reminder of the fact.

If the soil is contaminated then using organic growing practices won’t be as effective at eliminating contaminants.

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Consumerlab.com has recently found A LOT of arsenic contamination in flaxseeds. Even many organic brands are contaminated. FYI...organic is not a guarantee against heavy metal contamination, especially considering how corrupt US politicans, and regulators are.

This is a growing problem, and my best is that most of our food supply is contaminated by one of either arsenic, lead, mercury, or cadmium. Sometimes, it's low levels and not enough to trigger our laughable US regulations but still high enough to harm your health in the middle to long run...and definitely do damage to fetuses and children.

Dont forget microplastics contamination, foreverchemicas, PCB, etc.

Yeah...our world has become a toxic soup. Those trying to be toxin free are really playing a losing game. As the problem gets more widespread and the costs to fix get more expensive, eventually we will stop trying. Deregulation is sort of already there. Not saying dont try, but just be aware...you will lose.

History need not repeat itself. That's why global health research tends to have two branches - metrics and implementation. We have the metrics, so now we have to hope that policymakers can cooperate with the implementation experts.

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Agreed. It's their prerogative to have this mindset but i wouldn't necessarily endorse it. I think that not forgetting someone's transgression, letting it creep always in the back of your mind when building/rebuilding a relationship with them, kind of ruins the purpose of forgiveness. Don't mistake my words, i'm not saying you shouldn't build and enforce boundaries, and take measures if broken, but setting something for failure beforehand, it's as the previous redditor pointed out quite a clear example of self-fulfilling prophecy.

Yes I recognize that I will die early.

The study’s point was that positive attitude resulted in healthy habits

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"Just Asking Questions" aka "JAQ'ing off" is a common bad-faith argument used by those lying about their intent.

They occurred in Oklahoma to a much greater degree, and the Oklahoma Geological Survey (the state level USGS) published information demonstrating it was the fault of fracking.

If course, that was after oil companies (specifically Harold Hamm) and the University of Oklahoman's President, David Boren, attempted to stop them from publishing.

A quick source for the political interference: https://stateimpact.npr.org/oklahoma/2015/04/09/oil-billionaire-sought-meeting-with-ou-president-boren-on-oklahoma-quake-research-as-far-back-as-2011/

“COVID-19 magnified the polarisation and persistent social, economic, and racial inequities that already existed across US society, but the next pandemic threat need not do the same. US states that mitigated those structural inequalities, deployed science-based interventions such as vaccination and targeted vaccine mandates, and promoted their adoption across society were able to match the best-performing nations in minimising COVID-19 death rates. These findings could contribute to the design and targeting of clinical and policy interventions to facilitate better health outcomes in future crises.”

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They used 22 protein levels to assess an aging index called SASP:

Here are the 22 proteins:

> As in our previous studies28,30, the 22 proteins included in the SASP index used in the present study are IGFBP-6, IGFBP-2, MIP-1β, IL-1β, GMC-SF, PLGF, Angiogenin, MIF-1, MIP-1α, Gro-α, IL-6, MCP-4, Gp130, ICAM-1, MCP-1, IL-8, MIP-3 α, Osteoprotegerin, TIMP-1, uPAR, TNFRI and TNFRII. The raw values were log transformed and standardized to z scores, and the SASP index for each participant was calculated

> Cellular senescence11 has emerged as a pivotal hallmark of the biology of ageing. It is a complex stress response in which cells irreversibly lose their proliferative capacity, become resistant to apoptosis12 and develop a multicomponent secretory phenotype13, referred to as the senescence-associated secretory phenotype (SASP)12. The SASP includes proteins involved in cycle control, intercellular communication, the immune-inflammatory response and tissue remodelling14. Under non-pathological conditions, SASP proteins are essential for embryonic development and tissue patterning throughout life15. However, the accumulation of senescent cells and the increased secretion of SASP proteins with age is linked to tissue deterioration and the emergence of physical disorders prevalent in older adults16. Human and animal studies found that the increased expression of SASP proteins drives multiple age-related phenotypes, such as atherosclerosis17, osteoarthritis18, cancer19, kidney dysfunction20 and a shortened health span21. In humans, an increase in SASP proteins is related to obesity, cardiometabolic dysregulation22 and frailty14. Several studies characterized the role of cellular senescence and SASP proteins in the brain. Aged microglia, astrocytes and neurons exhibit various features of senescence, including the expression of SASP proteins23,24,25.

> While the cellular source of SASP proteins is unknown, some evidence suggests that the SASP index is relevant to brain health and that brain cells express SASP proteins23,24,25. In ageing and psychiatric disorders, the blood–brain barrier permeability is increased71, leading to an enhanced passage of proteins. Some studies suggest that plasma from old mice accelerates brain ageing in young mice72, and senolytic interventions targeting the periphery alleviate the effect of SASP proteins on the brain71.

Unknown !

Blood brain barrier permeability increased.

Perfectly understandable. It is a _very_ old clip!

I think the paper basically hints that it’s a potential cause of long Covid but the exact mechanism is not understood at this point.

>… will not only provide new strategies to fight SARS-CoV-2 in the acute phase, but also pave the way for unravelling the molecular basis of long COVID for its intervention.