Recent comments in /f/science

UnionOfSexWorkers t1_jdlly1g wrote

Ignore the idiots replying to you. This is one of the best takes on the matter I have seen in history.

When trust is broken aand a person comes back to you asking for forgiveness very quickly after breaking that trust clearly the person has not made any substantial changees in who they are as a person. Therefore we have to always keep our guard up...until the person has demonstrated over years, YES YEARS, that they have made this substantial change. That person will probably revert back to that dickheaded behaviour within 3 or 4 weeks, just give it some time.

If the person never does that dickheaded thing again in like 3 or 4 YEARS!? Well then congratulations! You've met someone who actually gives a damn about self-reflection and about you!

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BananaResearcher t1_jdllrpa wrote

From the authors, my emphasis

>Epigenetic alteration is known to exert long-term effects on gene expression and phenotypes37,38. Given the increasingly realized high incidence of post-acute SARS-CoV-2 sequelae (long COVID39), understanding the viral impacts on host chromatin and epigenome will not only provide new strategies to fight SARS-CoV-2 in the acute phase, but also pave the way for unravelling the molecular basis of long COVID for its intervention.

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UnionOfSexWorkers t1_jdll84j wrote

same. I would go as far as to say that Maslow's hierarchy is wrong. Humans NEED genuine and gainful and loving interaction with at least one other human or with some group of humans JUST as we need food and water.

Has anyone else noticed the correlation that exists between heightened suicide rate, low population density, and lack of mental health care funding?

...something funky going on there I'll tell you what!...

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BananaResearcher t1_jdlku8r wrote

Lots of viruses make use of the host's DNA for their own purposes. This study looked at how SARS-CoV-2 affected host DNA, on a large scale. [more in-depth: DNA is a giant, giant molecule. It's so big that its overall organization itself is really important and affects all kinds of things. A very simple example is that expression of a certain gene may rely on activation of a region on the DNA that is, in 1-dimension, extremely far away. But just like you can loop a rope back on itself to bring two points close together, these points can be extremely far in 1 dimension (along the DNA chain) but right next to each other in 3 dimensions.] This study found that SARS-CoV-2 does indeed modify infected cells' DNA on large scales, and this is important not just for acute infection but can cause lasting impacts after the infection is cleared.

ELI5: The virus bends the DNA around so the cell can't fight the virus as effectively

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Flimsy_Tooth_4443 t1_jdlkjs5 wrote

Are you suggesting we spend money to save lives and prevent catastrophe?

Don't be ridiculous. It will be used to bring "peace" to any countries which don't comply with US hegemony having thr audacity to have valuable materials on their land.

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weird_elf t1_jdlje36 wrote

>Here we characterized the 3D genome and epigenome of human cells after
SARS-CoV-2 infection, finding widespread host chromatin restructuring
that features widespread compartment A weakening, A–B mixing, reduced
intra-TAD contacts and decreased H3K27ac euchromatin modification
levels. Such changes were not found following common-cold-virus
HCoV-OC43 infection.

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