Recent comments in /f/science

artemisodin t1_jclgrmc wrote

Absolutely this. The label will have what your doctor prescribed. Sometimes doctors may request a different frequency than normal, in which case a pharmacist will call and clarify. The doctor may agree and change the prescription, but what is on the label is what the doctor wrote or adjusted to verbally.

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Aeseld t1_jclfzkr wrote

Honestly, your comments keep disappearing now. So yeah, not going to get anywhere.

But... You're factually wrong here. And refusing to accept it for some reason. Myocarditis does not always lead to tissue damage. This is a fact. So yeah, mild inflammation and tissue damage are not the same thing. Unless you're going from tissue damage causing mild inflammation.

That's a cut or scrape, not myocarditis.

Myocarditis is the inflammation. If severe, it can cause tissue damage. Mild, does not generally cause tissue damage.

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Revenge_of_the_User t1_jclfc3c wrote

My roomie works in a warehouse and his thought pattern under load is that if he takes a break, hes just going to have to do all that work anyway the next day, in addition to the rest of it.

So he cant enjoy days off, even if he got them. Its bonkers.

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Aeseld t1_jclef77 wrote

Honestly, it feels like this statement has cause and effect reversed.

Tissue damage always has inflammation associated with it. The healing process. Tissue damage causes inflammation.

Inflammation does not always have tissue damage associated with it though. You've worded it a little poorly to make that point in the context of your other comments.

Plus, myocarditis does not always have tissue damage associated with it. Especially mild cases.

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SwankyPants10 t1_jclco0z wrote

This makes no sense, the directions on your prescription label would be exactly what the doctor prescribed on the prescription. If they aren’t, then what the doctor is telling you to do and what they are writing on the script are not lining up.

There are often multiple dosages, frequences, etc in which a medication can be taken. This is why the prescribed dose often does not match what you may see on manfacturer monographs or online.

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The_Humble_Frank t1_jclcgmf wrote

its the natural wear down of any operational machine. you can't run a machine without creating wear.

Unlike strictly mechanical machines that are repaired and maintained by an independent operator, electrochemical-mechanical (aka Biological) machines, continuously gradually repair themselves with micro-patchwork fixes instead of whole component changes (though to a limited extent that is possible now with the aid of independent operators, called surgeons and medical teams), and the rate at which those fixes occur happens varies on the available resources, how easily those resource can reach the area (good luck on joint repair), what else in the total system needs repair, and how good the total system is overall operating.

But the repair systems themselves also incur damage, and poor patchwork makes future repairs more difficult. the ability to process materials lessens, the marrow creating the biochemical slurry that transfers resources throughout the system lessens in quality as damage builds up. Harder to repair systems get filled with quick filler scar tissue that doesn't properly mimic the function of the damaged tissue, and eventually one or more of dozens of critical systems can no longer maintain to operations at a minimum necessary levels of function, creating cascading terminal stresses on the remaining functioning systems.

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qleap42 t1_jclbsut wrote

That sounds like something you would have to discuss with your pharmacist about. Many times pharmacists know more about the drugs than doctors do. But dosage and frequency are usually set by the doctor. If the doctor says otherwise I would talk to your pharmacist to see why they had it different.

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Aeseld t1_jclb8vb wrote

Inflammation is a biological response of the immune system that can be triggered by a variety of factors, including pathogens, damaged cells and toxic compounds. These factors may induce acute and/or chronic inflammatory responses in the heart, pancreas, liver, kidney, lung, brain, intestinal tract and reproductive system, potentially leading to tissue damage or disease.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805548/

Note the word, potentially. As in, not 100%.

Cytokines modulate the immune response to infection or inflammation and regulate inflammation itself via a complex network of interactions. However, excessive inflammatory cytokine production can lead to tissue damage, hemodynamic changes, organ failure, and ultimately death [59, 60].

Again, excessive inflammation 'can lead' to tissue damage. Excessive. Can lead.

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