Recent comments in /f/science

Boaki t1_jci2389 wrote

Reply to comment by jubilant-barter in People with dark personality traits are better in finding novel ways to cause damage or harm others: Study reveals that people with more pronounced dark personality traits tend to have more malevolent creativity by DreamingForYouAlways

disagree. would much rather be up against competent malevolence. that's the guy that feels compelled to tell you his master plan while you're tied up, giving you a chance to get away.

the incompetent one ends up murdering all your loved ones while intending only to papercut you.

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Forgind1 OP t1_jci1yv9 wrote

Reply to Regulatory T Cells Mediate Proper Healing in Damaged Distal Tissues by Forgind1

Specific microbial signals induce the differentiation of a distinct pool of RORγ+ regulatory T (Treg) cells crucial for intestinal homeostasis. We discovered highly analogous populations of microbiota-dependent Treg cells that promoted tissue regeneration at extra-gut sites, notably acutely injured skeletal muscle and fatty liver. Inflammatory meditators elicited by tissue damage combined with MHC-class-II-dependent T cell activation to drive the accumulation of gut-derived RORγ+ Treg cells in injured muscle, wherein they regulated the dynamics and tenor of early inflammation and helped balance the proliferation vs. differentiation of local stem cells. Reining in IL-17A-producing T cells was a major mechanism underlying the rheostatic functions of RORγ+ Treg cells in compromised tissues. Our findings highlight the importance of gut-trained Treg cell emissaries in controlling the response to sterile injury of non-mucosal tissues.

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Reply to Regulatory T Cells Mediate Proper Healing in Damaged Distal Tissues by Forgind1

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OtherwiseOlive9447 t1_jchujyg wrote

Reply to People with dark personality traits are better in finding novel ways to cause damage or harm others: Study reveals that people with more pronounced dark personality traits tend to have more malevolent creativity by DreamingForYouAlways

I call it having a “bad idea machine” in one’s head. The ideas/desires are ego-syntonic, thrive in the absence of a conscience (super-ego), and is often hyper-activated by opportunity (natural disasters/access to large amounts of money), lack of parental supervision (for youths) or the perceived weakness/vulnerability of potential victims. For some of these people, scheming and planning are indistinguishable, and novel ideas can arise in some. The rest are stuck simply repeating well worn scams, which can still hurt others.

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