Recent comments in /f/science

CultCrossPollination t1_jc5ypvm wrote

Reply to comment by barryman5000 in Cancer researchers show introducing bacteria to a tumour’s microenvironment creates a state of acute inflammation that triggers the immune system’s primary responder cells to attack rather than protect a tumour. by unswsydney

Thanks for calling the originally described hypothesis/context. The use of microbes is nothing new, see also oncolytic viruses. The main difference is that we currently know a lot more about cancer and the importance of the interplay with the immune system. So I am still curious to see what further research this might bring, and if we can improve current strategies. Although I am also careful for enhancing innate inflammation.

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thekux t1_jc5yklt wrote

Reply to Confirmed: Global floods, droughts worsening with warming by besselfunctions

There’s no science in this statement. They keep changing their stories, too. They keep trying to say the desert southwest of the US and California is in a mega drought which it is not and hasn’t been in several hundred years. Now they’re trying to blame the mass of rain and snow fall on you guessed it global warming. If it snows too much, it’s global warming. If it rains too much is global warming. If it doesn’t rain is global warming. They only really believe people are stupid.

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Emu1981 t1_jc5uc8a wrote

Reply to comment by YawnTractor_1756 in Confirmed: Global floods, droughts worsening with warming by besselfunctions

>No wonder that despite things are overall maybe 10% worse, people perceive them to be 120% worse.

We had a record fire season in 2019 here in Australia where over thirteen million acres of bushland burned at temperatures hot enough to kill everything. We then had record rain and flooding events for the next few years. Now that El Nino is back in effect I expect that we will go back to record breaking bushfire seasons...

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Fixing_The_World t1_jc5njwq wrote

Reply to Cancer researchers show introducing bacteria to a tumour’s microenvironment creates a state of acute inflammation that triggers the immune system’s primary responder cells to attack rather than protect a tumour. by unswsydney

Thank you for sharing.

Taking it a step further, panels of common bacteria could be displayed to a sample of the patient's immune system. We could figure out which elicit the strongest response. Then use the antigens for tumor injection.

What they have done in the paper is a phenomenal idea and so simple.

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barryman5000 t1_jc5mrlp wrote

Reply to Cancer researchers show introducing bacteria to a tumour’s microenvironment creates a state of acute inflammation that triggers the immune system’s primary responder cells to attack rather than protect a tumour. by unswsydney

So we are getting back to Coley's Toxins?

It was a rather neat approach that I'm not sure ever got studied correctly. Coley never did a proper study and the idea of injecting anybody with bacteria that made them sick when radiation therapy was showing consistent results really killed any further research.

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