Recent comments in /f/IAmA
OneLostOstrich t1_jcnh9y7 wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Fascinating work. I'm surprised that there aren't more questions.
Can you share the latest in the process of restoring nerve damage or encouraging nerves to grow to a tissue or implanted material?
What about encouraging growth of collagen producing cells that decline as we age? Also, encouraging satellite cell division and promotion of apoptosis in cells that are not functioning normally.
dee615 t1_jcn8hd1 wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Very interesting! Are you familiar with the work of Dr.Neri Oxman, formerly of MIT?
Redleaded t1_jclyrgt wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hi Nazia, this sounds really interesting. What fabrication methods are you using to create these materials?
Ok-Feedback5604 t1_jclx2k8 wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
What do you think we can do to make the implant process affordable and accessible to all?
[deleted] t1_jcl2des wrote
Faptain__Marvel t1_jckuvw5 wrote
Reply to comment by Lout324 in We are Unemployed Professors, and we've been writing the things other people don't want to write for 12 years. AUA. by unemployedprofessors
It seems you don't like the answer, but the answer is pretty explicit.
If you can't beat 'em, join 'em.
belac1848 t1_jckpfrv wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hello, Nazia, and thank you for joining!
Question for you: With all the fringe group hubub surrounding "micro chipping" in COVID vaccines and such, has your research received any scrutiny, harassment, disapproval from those who worry about "surveillance" and the likes? Don't support their stance at all, but curious if the whole idea of putting new technology into the human body has received significant push back, especially from online groups, in the last, say, five years or so.
UniversityofBath OP t1_jcknccc wrote
Reply to comment by lil_kreen in Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hello. I'm not sure! I have never worked with magnetic materials but know that magnets have been used medically (externally) for example to control small robots that deliver drugs into the back of your eye. The brain and recreating electrical signals is very far from my research field I'm afraid!
lil_kreen t1_jckmv8z wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
There was some medically inadvisable biohackery going on with magnet capsules implanted into fingertips I remember from a while back. Thereafter reporting being able to feel electrical fields as they move/vibrate. A similar sort of neuroplasticity being the compass belt that pops up every so often. Is it possible to make a medically safe magnetic materials that could produce similar effects with enough responsivity where the brain can pick up and adapt to the stimuli?
UniversityofBath OP t1_jcklxws wrote
Reply to comment by Silver_Guarantee_764 in Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hello! I am not a clinical trial expert (though I often lean on wonderful colleagues who are!) but if we got to that stage with our materials (after rigorous tests in a laboratory environment) the clinical trials would test for both safety and efficacy. The design of what representative population group to test on would be the job of the trial design expert. It would also depend on whether we have designed a material that targets a specific disease or whether it's designed to repair injuries (blunt force trauma).
I would also add that different countries have slightly different pathways to design clinical trials. So what's FDA approved may not necessarily be EMA approved (European equivalent).
Silver_Guarantee_764 t1_jckl52d wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hi! I'm curious how this would end up going through clinical trials? Would it go through the same path of healthy then injured or would it go straight into injured?
UniversityofBath OP t1_jckkgyb wrote
Reply to comment by PeanutSalsa in Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hello! Some of the materials we create are designed to last (for example some I'm designing to create robot parts for humans) while others are designed to attract the cells and degrade as the cells take over (giving them the initial nourishment and room to grow and take over the space).
PeanutSalsa t1_jckk3oy wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
How does the lifespan of these materials measure up to organic materials of the same use already existent in the body?
UniversityofBath OP t1_jckiwx4 wrote
Reply to comment by CuriousRedPandaBear in Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
It was an accidental journey. I did my first degree in forensic science and came across a project that was trying to recreate the fingerprint ridges. I thought that was interesting and as I started to explore I realised you could create more than fingerprints. I started using materials that are readily available and then eventually landed on making my own.
CuriousRedPandaBear t1_jckifo5 wrote
Reply to comment by UniversityofBath in Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Thank you! Where did you interest in this start?
UniversityofBath OP t1_jckgz1g wrote
Reply to comment by Annual-Mud-987 in Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hi! Absolutely! Our vision is to one day be able to grow new tissues and maybe even organs one day for patients, using these materials and the patient's own cells. That would certainly reduce organ transplant lists....
UniversityofBath OP t1_jckgqy7 wrote
Reply to comment by Double_DD_250 in Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hi! Tissues in the body are composed of many different types of proteins. One of the designs I am currently working on replicates some of the ways nature puts these proteins together. By copying nature's 'design rules' we've been able to create our own novel materials. So the short answer to this long explanation is they are protein based (though not all of my designs are. It entirely depends on what we're trying to do).
An excellent question regarding the immune response. Part of this is trying to match what our body can already tolerate though this is difficult! My materials have shown low immune response so far though we are trying to probe that further currently and see if we can modify our materials to 'calm down' an inflammatory response too.
IAmAModBot t1_jckgf26 wrote
Reply to I’m Ellie Jarvis (she/her), a 2nd year PhD Student in the Department of Life Sciences at the University of Bath, UK. I research how female fruit flies drink alcohol to manage STIs. by UniversityofBath
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IAmAModBot t1_jckget2 wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
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Annual-Mud-987 t1_jckgbzu wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hi! Could these smart materials have any impact on organ transplants? It seems like it could be a helpful way to prevent the body rejecting the new organ if you're able to mimic the chemistry of the body
Double_DD_250 t1_jckg5v9 wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hi Nazia, your research sounds very interesting. What kind of "smart" materials are you currently using? How can you avoid triggering an immune response once these materials come in contact with the body?
ComfortableCurrent65 t1_jckfdjw wrote
Reply to I am Amit, ex-Head of Digital Marketing at Meta. I am here to talk about digital marketing, growing your business, switching careers, MBA, finding jobs, interviews or anything else related to marketing. AMA! by [deleted]
As Head of Digital marketing, what did your day look like?
UniversityofBath OP t1_jckf4y5 wrote
Reply to comment by CuriousRedPandaBear in Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
Hello! My materials are not currently being used in patients. It takes years to develop and refine the designs so they are suitable for implantation. This is then followed by strict regulatory tests and approvals before we go anywhere near a patient. All new healthcare technologies and drugs that are developed have to go through this process. My designs are still 'early stage' though I have been doing significant tests on them.
Regarding the second part of your question: cells decide how they will respond to materials by detecting physical and chemical changes around them. I study what would normally be present in healthy tissue and try to replicate these in my materials.
ComfortableCurrent65 t1_jckez0x wrote
Reply to I am Amit, ex-Head of Digital Marketing at Meta. I am here to talk about digital marketing, growing your business, switching careers, MBA, finding jobs, interviews or anything else related to marketing. AMA! by [deleted]
Pretend you're a digital marketing head at Meta or any company. You're tasked to hire 1 jr. digital marketing consultant/executive.
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You've one guy that's B-tech dropout, but used his remaining 2-3 years learning Content marketing, Copywriting, Marketing Funnels. He's got few clients from Upwork. So he has basically something to show for his proof of work.
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A proper marketing student. This guy passed every exam with top grades. He got his MBA too. And while studying, he attended 'workshops' or 'internships' with companies in touch with his college.
(Let's assume both are well behaved and likeable in the interview. Both are easy to work with and coachable.)
Who would you hire from these 1 & 2 based on their previous experience?
[deleted] t1_jcnhcxk wrote
Reply to Hello Reddit, I’m Nazia Mehrban, a Lecturer in Biotechnology at University of Bath. I design and build materials that are implanted into patients to repair or replace damaged tissues. by UniversityofBath
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